2-FMA HCL for sale
2-FMA HCl (2-Fluoromethamphetamine Hydrochloride) is a synthetic stimulant compound belonging to the phenethylamine and substituted amphetamine classes. Structurally related to methamphetamine, 2-FMA features a fluorine atom at the 2-position of the phenyl ring, which alters its pharmacological profile and potency. This compound is commonly studied for its potential stimulant effects, receptor activity, and metabolic properties.
In research environments, 2-FMA is valued for its stability, ease of handling, and well-documented synthesis route, making it an ideal reference standard for analytical applications. It is often used in forensic analysis, receptor binding studies, pharmacokinetics research, and in the development of structure–activity relationship (SAR) models.
This product is supplied as the hydrochloride salt for improved solubility and consistency in lab conditions. Researchers should ensure proper handling, storage, and documentation in accordance with applicable safety guidelines and institutional protocols.
⚗️ Specifications (Example Only – May Vary by Vendor):
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Chemical Name: 2-Fluoromethamphetamine Hydrochloride
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CAS Number: (Varies, not officially registered)
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Molecular Formula: C10H14FN·HCl
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Form: Crystalline powder
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Purity: ≥98% (lab-grade)
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Storage: Cool, dry place; protect from light and moisture
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Use: Research & analytical purposes only
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⚗️ 2-FMA HCl: Uses, Properties, and Manufacturing Process
✅ Uses of 2-FMA HCl
2-FMA HCl (2-Fluoromethamphetamine Hydrochloride) is a synthetic stimulant compound primarily used in research and analytical laboratories. It belongs to the substituted amphetamine class and features a fluorine atom at the 2-position of the phenyl ring, which gives it a distinct pharmacological profile compared to its structural analogs like methamphetamine or amphetamine.
🔬 Common Research Uses Include:
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Neurochemical studies on dopamine and norepinephrine transporters
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Receptor binding assays to investigate structure–activity relationships (SAR)
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Pharmacokinetics and metabolic pathway research
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Forensic toxicology and drug screening development
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Mass spectrometry and GC-MS reference standard calibration
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Comparative behavioral studies using rodent models (in licensed settings)⚠️
✅ Physical & Chemical Properties of 2-FMA HCl
Property | Details |
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Chemical Name | 2-Fluoromethamphetamine Hydrochloride |
IUPAC Name | 1-(2-Fluorophenyl)-N-methylpropan-2-amine HCl |
Molecular Formula | C10H14FN·HCl |
Molecular Weight | ~203.68 g/mol |
Form | White crystalline powder |
Solubility | Soluble in water and alcohols |
Stability | Stable under normal lab storage conditions |
Storage Conditions | Cool, dry place away from light |
CAS Number | Not officially assigned (varies) |
Class | Phenethylamine / Substituted Amphetamine |
2-FMA HCl is often supplied in its hydrochloride salt form to improve solubility, handling, and stability in laboratory environments. It is known for producing stimulant-like activity similar to that of amphetamine derivatives in controlled research settings.
✅ Manufacturing Process of 2-FMA HCl (For Academic Reference Only)
The synthesis of 2-FMA HCl involves a multi-step organic synthesis process that requires advanced knowledge in synthetic chemistry and should only be conducted in licensed, regulated laboratories by professionals.⚠️
🔬 Step-by-Step Overview (Academic Only)
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Starting Material:
The process typically begins with 2-fluorophenylacetone (or another suitable fluorinated aromatic precursor). -
Reductive Amination:
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The ketone is reacted with methylamine under reductive amination conditions (using a reducing agent such as sodium cyanoborohydride or hydrogenation over a catalyst) to form the secondary amine, 2-fluoromethamphetamine.
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Salt Formation:
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The freebase compound is then converted into its hydrochloride salt by bubbling dry HCl gas through an anhydrous ether or ethanol solution, or by using aqueous HCl followed by crystallization.
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Purification:
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The resulting 2-FMA HCl is recrystallized and purified using standard lab techniques such as solvent washes and vacuum drying to remove impurities.
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Characterization & Testing:
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The final compound is characterized via NMR, IR, GC-MS, and HPLC to verify identity, purity, and consistency.
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✅ Safety and Legal Considerations
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2-FMA HCl may be considered a controlled substance or analog in certain jurisdictions. Researchers must ensure they comply with local laws, licensing requirements, and institutional protocols.
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Proper personal protective equipment (PPE) and ventilation must be used when handling the compound.
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Dispose of any waste materials in accordance with hazardous chemical disposal regulations.
📌 Final Notes
2-FMA HCl continues to be of significant interest in chemical and neuropharmacological research due to its unique structure and potential insights into central nervous system stimulants. Its solvent-free synthesis (via reductive amination) and well-defined purity profile make it a useful candidate for in vitro analysis, receptor profiling, and analytical method development.
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